Harnessing the power of Premium Cold Plasma to penetrate biofilm, destroy resistant bacteria,1 and accelerate healing.2,3
Even with advanced therapies, chronic infection remains difficult to treat
Topical therapies can’t penetrate the wound,4 other plasma technologies lack the energy or density to reach infection at its source,5 and biofilm shields bacteria from antibiotics,6 making them up to 1000x more resistant to antibiotics.7
Clear infection at its source with Premium Cold Plasma
Premium Cold Plasma is created when proprietary microwave technology is applied to argon gas, producing a mix of ions, electrons, and reactive particles that target bacteria directly.
Premium Cold Plasma uses a unique physical mode of action to penetrate biofilm and target bacteria directly,1 with studies showing no primary or secondary resistance can develop in gram-negative, gram-positive, or biofilm-protected bacteria.1
01
Bacterial
destruction1
Plasma components create micropores in the cell wall, damaging internal structures.
02
Biofilm
breakdown
Biofilm is penetrated, exposing hidden bacteria to further attack.1
03
Tissue
protection
Healthy cells remain unharmed as their membranes are more robust.7
Not all plasma is the same
Every device creates a unique plasma with its own energy density, stability, and ability to act on infection. Other plasma technologies may kill bacteria, but not all have the required energy and density to kill those in chronic infections.
The unique ‘plasma cocktail’ is influenced by both the method of plasma generation and the choice of carrier gas, making each plasma device unique.
The most advanced cold plasma technology
The power of plasma lies in its density. Adtec’s Premium Cold Plasma is created using 2.45 GHz microwave technology and pure argon gas to produces a cool high-density plasma stream rich in reactive species. Premium Cold Plasma ruptures bacterial cell walls and breaks through biofilm more effectively than other plasma technologies.8
Why density matters
The power of plasma lies in its density. A denser plasma delivers more reactive species, driving deeper and more effective bacterial destruction.
More energy
High-density plasma produces stronger reactives.
Deeper reach
Penetrates biofilm and hidden bacteria.1
Better results
Accelerates healing2,3 and reduces bacterial load.1
clears infection at the source
SteriPlas uses Premium Cold Plasma to penetrate biofilms, destroy resistant bacteria,1 and accelerate healing2,3 more effectively than standard therapies.
Reduces bacterial load by 73.5%1
Decreases wound size and depth by up to 100%9
Consistently outperforms antibiotics1
Discover SteriPlas
References
1. Isbary G, Heinlin J, Shimizu T, et al. Successful and safe use of 2 min cold atmospheric argon plasma in chronic wounds: results of a randomized controlled trial. Br J Dermatol. 2012;167(2):404-410. doi:10.1111/j.1365-2133.2012.10923.x
2. Heinlin J, Zimmermann JL, Zeman F, et al. Randomized placebo-controlled human pilot study of cold atmospheric argon plasma on skin graft donor sites. Wound Repair Regen Off Publ Wound Heal Soc Eur Tissue Repair Soc. 2013;21(6):800-807. doi:10.1111/wrr.12078
3. Isbary G, Stolz W, Shimizu T, et al. Cold atmospheric argon plasma treatment may accelerate wound healing in chronic wounds: Results of an open retrospective randomized controlled study in vivo. Clin Plasma Med. 2013;1(2):25-30. doi:10.1016/j.cpme.2013.06.001
4. Stuermer EK, Plattfaut I, Dietrich M, et al. In vitro Activity of Antimicrobial Wound Dressings on P. aeruginosa Wound Biofilm. Front Microbiol. 2021;12. doi:10.3389/fmicb.2021.664030
5. Data on file.
6. Jager NGL, van Hest RM, Lipman J, Roberts JA, Cotta MO. Antibiotic exposure at the site of infection: principles and assessment of tissue penetration. Expert Rev Clin Pharmacol. 2019;12(7):623-634. doi:10.1080/17512433.2019.1621161
7. Zhao A, Sun J, Liu Y. Understanding bacterial biofilms: From definition to treatment strategies. Front Cell Infect Microbiol. 2023;13:1137947. doi:10.3389/fcimb.2023.1137947
8. Heinlin J, Isbary G, Stolz W, et al. Plasma applications in medicine with a special focus on dermatology: Plasma medicine. J Eur Acad Dermatol Venereol. 2011;25(1):1-11. doi:10.1111/j.1468-3083.2010.03702.x
9. Biomed P. Anti-biofilm activity demonstrated following treatment with a novel plasma device | Perfectus Biomed. November 9, 2015. Accessed October 18, 2023. https://perfectusbiomed.com/anti-biofilm-activity-demonstrated-following-treatment-with-a-novel-plasma-device-booth-r-cutting-k-f-and-westgate-s-j-2015/
10. Moelleken M, Jockenhöfer F, Wiegand C, Buer J, Benson S, Dissemond J. Pilot study on the influence of cold atmospheric plasma on bacterial contamination and healing tendency of chronic wounds. J Dtsch Dermatol Ges J Ger Soc Dermatol JDDG. 2020;18(10):1094-1101. doi:10.1111/ddg.14294